Conclusions

Despite significant research and investment in resources, the pathogenesis of cerebral aneurysms remains to be completely elucidated. Early investigators argued in favor of a congenital etiology of aneurysmal formation, including hypotheses involving the medial defects of Forbus and other possible sources of weakness inherent to vessel walls at birth. Subsequent researchers focused on developmental factors in aneurysmal formation, including such mechanical factors as hypertension, turbulence, and resonance. Interestingly, current research has refocused on a congenital etiology, namely genetic factors, that might predispose some individuals to aneurysmal formation. It is likely that a combination of congenital and developmental factors participates in aneurysmal formation and rupture, and it is hoped that further efforts to understand these factors will lead to improved treatment and diagnostic modalities to improve the morbidity and mortality of patients with intracerebral aneurysms.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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