Conclusions And Future Directions

In conclusion, PET allowed prediction of malignant MCA infarction at an early state and long before determinations of ICP and PtO2 or microdialysis recorded the ongoing progression and detrimental pathophysiologic changes that accompany the critical stage of clinical deterioration. The combination of these methods helps to identify patients at risk for formation of space-occupying edema and could be useful for the selection of patients who might benefit from invasive inter-ventional therapeutic strategies.

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