Global Outcome Scales

The modified Rankin Scale (mRS) and Glasgow Outcome Scale (GOS) (Table 6) are perhaps the two most common measures of global outcome used in aSAH research. The mRS (15) is increasingly being adopted as a primary endpoint in stroke clinical trials and has significant advantages over the GOS for evaluating aSAH patients because it has a smaller ceiling effect than the GOS. The scale describes death and 6 grades of disability and is able to describe the full spectrum of limitations after injury. The highest level includes patients who have no disability or symptoms related to their hemorrhage. Although inter-rater reliability meets criteria for satisfactory clinical assessment, there is room for improvement (15). The mRS has been used extensively in aSAH research. The GOS (16) was originally developed as an outcome scale for traumatic brain injury. Although it is still widely used, the categories tend to be broad, making it difficult to capture subtle improvements. In contrast to the mRS, the highest level of outcome on the GOS includes independent patients who continue to suffer from mild physical disability. However, it is well documented that patients in this best level of outcome may still suffer from devastating cognitive impairment (17).

Metabolism Masterclass

Metabolism Masterclass

Are You Sick And Tired Of All The Fat-Burning Tricks And Trends That Just Don’t Deliver? Well, Get Set To Discover The Easy, Safe, Fast, And Permanent Way To Mega-Charge Your Metabolism And Lose Excess Fat Once And For All! This Weight Blasting Method Is Easy AND Natural… And Will Give You The Hot Body And Killer Energy Levels You’ve Been Dreaming Of.

Get My Free Ebook

Post a comment