Infectious Aneurysm

Originally called "mycotic" aneurysms by Osler at a time when infectious processes were labeled as such, infectious aneurysms are actually more commonly caused by bacterial rather than fungal infections. They comprise approximately 5% of intracranial aneurysms. It is common for multiple infected aneurysms to occur simultaneously, and they more commonly occur in distal branches of the middle cerebral artery. Formation of infectious aneurysms occurs via multiple pathways, but the process is believed to begin in the adventitia and progress toward the lumen (152). Septic emboli, often from bacterial endocarditis, become lodged in the vasa vasorum, followed by inflammation and destruction of the vessel wall.

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