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Abbreviations: MAPK, mitogen-activated protein kinase; cGMP, cyclic guanosine monophosphate.

Abbreviations: MAPK, mitogen-activated protein kinase; cGMP, cyclic guanosine monophosphate.

the incidence of angiographic vasospasm, include the inhibition of vascular proliferation. In fact, a number of other diverse therapies that ameliorate vasospasm all share this feature (Table 1). The overall control of SMC function and the regulation of its responses to changing environmental cues are extremely complex activities that are just beginning to be understood.

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