Intravenous Cold Saline

Iced normal saline infusions have been shown to be effective at rapidly reducing core temperatures (65-69). Healthy volunteers were cooled by 2.5°C within an hour of starting a 30-min infusion of 4°C saline (40 mL/kg) after neuromuscular block with vecuronium and general anesthesia (67). Twenty-two patients who were resuscitated from cardiac arrest were cooled by 1.7°C, with 30 mL/kg of 4°C lactated Ringers solution given over 30 min (65). All of these patients received neuromuscular blocking agents. In a similar study, 2 L of 4°C saline was given over 20 to 30 min following return of spontaneous circulation after cardiac arrest (68), resulting in a mean drop of 1.4°C 30 min after initiation of infusion. This drop in temperature did not affect the left ventricular ejection fraction, vital signs, or coagulation parameters.

Recently, a group that studied the feasibility of inducing hypothermia in a prehospital setting, using an infusion of 30 mL/kg of "ice-cold" Ringer's solution given at a rate of 100 mL/min to comatose patients with out-of-hospital cardiac arrest, was able to reduce core temperature from 35.8°C at onset of infusion to 34°C on arrival to hospital (69). Together, these studies demonstrate that the use if intravenous cold saline is a safe, easy-to-use and effective method of inducing systemic hypothermia.

Metabolism Masterclass

Metabolism Masterclass

Are You Sick And Tired Of All The Fat-Burning Tricks And Trends That Just Don’t Deliver? Well, Get Set To Discover The Easy, Safe, Fast, And Permanent Way To Mega-Charge Your Metabolism And Lose Excess Fat Once And For All! This Weight Blasting Method Is Easy AND Natural… And Will Give You The Hot Body And Killer Energy Levels You’ve Been Dreaming Of.

Get My Free Ebook


Post a comment