Intraventricular Thrombolysis

Intraventricular hemorrhage occurs in 40% patients with ICH and 15% with Subarachnoid hemorrhage (SAH), adding to the already elevated morbidityand mortality of these diseases (17). Based on a preliminary report that intraventricular urokinase might significantly improve 30-day survival in IVH patients (18), a double-blinded, placebo-controlled, multicentered study using intraventricular thrombolysis to treat IVH was undertaken (19). The results of an ongoing study assessing the effect of intraventricular thrombolysis on neurologic outcome of ICH patients are eagerly awaited before this intervention can be incorporated into management of patients with IVH.

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