Intracerebral hemorrhage (ICH) is the most lethal form of stroke, with mortality estimates ranging from 23% to 58% in various modern series (1-3 ) . The study of the characteristics, behaviors, and outcomes of ICH has progressed through 3 phases. Early reports concerning outcome were largely descriptive and focused on specific lesion locations. These reports often identified specific clinical findings of prognostic significance. Subsequently, the advent of more sophisticated statistical analysis allowed for the development of multivariate models that provided powerful predictive instruments for large classes of ICH patients. These models have proven useful for estimating the effects of certain characteristics in heterogeneous patient groups (e.g., supraten-torial hemorrhages), but they often lack specific clinical detail. Most recently, the prognostic significance of individual factors has been confirmed by clinical trial and observational data from larger data sets. This chapter describes the prognostic information gleaned from these 3 phases.

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