Mri In Stroke Research

New imaging techniques, especially MRI, can provide a translational link between experimental advances in acute stroke research and clinical applications (33). MRI can identify markers of "tissue at risk" (to link therapy to tissue pathobiology); demonstrate the effects of cerebral reperfusion on the underlying vascular pathology, cerebral blood flow, and blood-brain barrier (BBB) integrity; and establish parameters for dose, duration, and time window to optimize drug delivery to the ischemic area. New knowledge in these areas and the use of MRI in therapeutic studies can lead to improved patient selection and evaluation of drug activity in clinical trials.

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