Other Prophylactic Measures

The implantation of prolonged release implants at the time of surgical repair of the aneurysm might help reduce the incidence of vasospasm. Preliminary work with implants impregnated with papaverine (82) and nicardipine (83) is promising. A small trial with enoxaparin suggested a reduction in DID (84). A more aggressive approach, the prophylactic use of transluminal balloon angioplasty in patients with Fisher Grade 3 SAH, was reported to markedly reduce the rate of vasospasm in this high-risk group of patients (85 ).

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