Leiner's disease (erythroderma desquamativum) is a disorder that usually begins during the first few months of life and is characterized by severe generalized seborrheic dermatitis, intractable diarrhea, recurrent infections (usually Gram-negative organisms), and marked wasting and dystrophy. The dermatitis involves an intense erythema of the entire body and extensive large, yellow, greasy scales affecting large portions of the body surface. These scales are desquamative, and large skin areas may slough. IgE levels are typically normal and eosinophils are not present. The exact etiology of this disease is unknown but a familial form exists and has been associated with dysfunction of the fifth component of complement (C5).
Langerhans' cell histiocytosis disease is a lethal disorder that is a spectrum of diseases affecting the reticuloendothelial system. A subset of that spectrum, previously known as Letterer-Siwe disease, involves a dermatitis that displays features of both seborrhea and AD. The eruption usually begins on the scalp and postauricular areas as a scaly, erythema-tous rash resembling seborrhea. The rash progresses to involve the trunk with dark, crusted papules that may be associated with petechiae or purpuric papules.
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.