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Longevity Health and Wellness Protocol

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Recently developed molecular and genetic interventions have been successful in controlling aging and longevity. Even though these lines of investigation hold great potential, studies using CR in rodents and nonhuman primates continue to provide valuable information. Because the effects of CR on aging processes, age-associated diseases, and longevity could be universal across species, this nutritional paradigm would have similar eVects in humans. We believe that the genes or signal cascades altered by CR could be the principle target for generating novel mutant animal models that show suppressed aging processes and live longer. Moreover, CR mimetics, which are applicable in humans, may represent one strategy to modulate aging processes and longevity. Therefore, we emphasize the importance of dietary and calorie interventions and the interpretation of their eVects in aging research, particularly in rodents, to humans.

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