With regard to neuromuscular transmission list all locations for acetylcholine receptors

ACh receptors are found in several areas:

  • About 5 million ACh receptors per neuromuscular junction (NMJ) are located on the postjunctional motor membrane.
  • Prejunctional receptors are present and influence the release of ACh. The prejunctional and postjunctional receptors have different affinities for ACh.
  • Extrajunctional receptors are located throughout the skeletal muscle in relatively low numbers owing to suppression of their synthesis by normal neural activity. In cases of traumatized skeletal muscle or denervation injuries, these receptors proliferate.

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