Diet and gene interactions

As we have seen, carcinogenesis is a prolonged multi-stage process which usually occurs over many years. Because of its complexity there are, in principle, many critical steps at which food-related substances or metabolic processes may interact with the sequence of events so as to accelerate, delay or even reverse it. Diet-related anti-carcinogenesis can usefully be classified into blocking mechanisms, which operate during the initiation phase of carcinogenesis, and suppressing mechanisms,...

Grapes and wines

Chemical Structure Narcotics

Antioxidants in grapes (Vitis vinifera) and grape juices have been recently reviewed by Frankel and Meyer.47 Both fresh grapes and commercial grape juices are a significant source of phenolic antioxidants. Extracts of fresh grapes inhibited human LDL oxidation from 22 to 60 and commercial grape juices from 68 to 75 when standardised at 10 M gallic acid equivalents (GAE).3839 The antioxidant activities of grapes and grape juices were comparable to those found for wines (Table 10.2).40 The LDL...