From Cancer Research to Anti Apicomplexa

Members of the phylum Apicomplexa account for some of the most debilitating infections of humans and livestock. Malaria, caused by Plasmodium sp., is undoubtedly the most important infectious disease and a major cause ofdeath in developing countries. Other infections by apicomplexan parasites such as Toxoplasma gondii, Cryptosporidium parvum and Babesia sp. are usually asymptomatic in humans but become life-threatening diseases in immune-compromised patients. The latter species, as well as...

Conclusion

The discovery of novel drugs for parasitic diseases is a high-risk, expensive, and lengthy process 22 . The past few years have seen increased financial and infrastructural support for drug discovery and development for parasitic diseases by academic institutes, PPPs, and the pharmaceutical industry 3, 5 . Already this has led to imaginative, comprehensive and dynamic drug discovery and development pipelines (even in the face of sometimes modest financial backing) when compared to those...

Drug Discovery Initiatives to Accelerate the Development of Novel Anti Parasitic Drugs for Humans and Animals

Infectious diseases, including those caused or transmitted by parasites, are responsible for substantial morbidity and mortality worldwide and affect several billion people globally, particularly in developing countries 1 . Until recently, infectious diseases were viewed as a problem of the past however, the emergence of drug-resistant organisms makes the need for new drugs or vaccines more important than ever before. Moreover, as these diseases predominantly afflict inhabitants of poor...