Genetic Diversity Of

Hiv Genetic Diversity

Human immunodeSciency virus is a primate retrovirus of the Lentivirinae family, a group that shares the ability to infect their host chronically, and progressively damage the hostOs immune system. Genetic variation of HIV is extremely high as a consequence of the rapid turnover of HIV virions (2). Individuals infected with HIV maintain a substantial viral burden during the entire course of infection (3,4). Related strains share genetic similarity, as expressed by the sequence of component...

Molecular Epidemiology By Region Africa

Africa has been the region most severely affected by the HIV AIDS epidemic. The high prevalence of HIV in many parts in Africa, the wide distribution of HIV-1 and HIV-2 subtypes (Fig. 3.2), and the genetic variation within subtypes, suggest that HIV has been on that continent for a relatively long time compared with other regions (14,51,52). However, extensive demographic changes with shifts from rural to urban areas and numerous population displacements from migrant labor and civil...

Susan M King Mary Lou Lindegren and Martha F Rogers

The Srst cases of the acquired immunodeSciency syndrome AIDS in children were reported to the Centers for Disease Control and Prevention CDC in 1982. Since that time nearly 9,000 cases of AIDS in children aged less than 13 years and over 5,000 deaths in children under 15 years have been reported 1 . Perinatal transmission of the human immunodeSciency virus HIV accounts for 91 of the pediatric AIDS cases and almost all new HIV infections in children 1 . Based on data from the National Survey of...