Liver Cancer

Seven studies that have examined obesity and liver cancer or hepatocellular carcinoma (HCC) found excess relative risk in both men and women in the range of 1.5 to 4.0 (3,34,95,96,132,155,158); however, two studies did not find any suggestion of an increased risk (36,131). Taken together, these studies suggest that obesity increases the risk of liver cancer, but the magnitude of the observed relative risk from existing studies is not consistent.

Obesity, and especially visceral adiposity, is strongly associated with nonalcoholic fatty liver disease (NAFLD), a chronic liver disease that occurs in nondrinkers but that is histologically similar to alcohol-induced liver disease (159). NAFLD is an emerging clinical problem among obese patients and is now recognized as the most common cause of abnormal liver tests (160). Disorders of glucose regulation are significantly associated with NAFLD, indicating that insulin resistance is the link between NAFLD and metabolic diseases (160). NAFLD is characterized by a spectrum of liver tissue changes ranging from accumulation of fat in the liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and HCC at the most extreme end of the spectrum. Progression to NASH appears to represent the turning point from a seemingly nonprogressive condition to fibrosis, necrosis, and inflammation, and multiple cellular adaptations to the resulting oxidative stress (159). Visceral adiposity likely contributes to the risk of HCC by promoting NAFLD and NASH.

5 Ways To Get Rid Of The Baby Fat

5 Ways To Get Rid Of The Baby Fat

Many women who have recently given birth are always interested in attempting to lose some of that extra weight that traditionally accompanies having a baby. What many of these women do not entirely realize is the fact that breast-feeding can not only help provide the baby with essential vitamins and nutrients, but can also help in the weight-loss process.

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