Inflammation And Cardiovascular Risk

Inflammation is an intrinsic part of the pathogenesis of atherosclerosis and cardiovascular disease (CVD)1. Accumulation of inflammatory cells in the vessel wall and predominantly in so-called vulnerable plaques suggests that the most vulnerable sites in the vessel wall have the most intense inflammatory activity2'3. Inflammatory cells whether in the vessel wall or the circulation produce a number of inflammatory proteins called cytokines which are central to the proinflammatory response of the vessel wall and the systemic acute phase response. Inflammatory cytokines such as interleukin-1 (IL-1) and interleukin-6 (IL-6) stimulate the production of C-reactive protein (CRP) predominantly by the liver, but also by endothelial and smooth muscle cells in the vessel wall (Figure 6.1).

Your Heart and Nutrition

Your Heart and Nutrition

Prevention is better than a cure. Learn how to cherish your heart by taking the necessary means to keep it pumping healthily and steadily through your life.

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