Example Visualization of Gene Clusters in Bladder Cancer

Figure 6.8 is a visualization of the most important genes (selected by their co-variance to the progression of the disease) in DNA microarray measurements in bladder cancer patients.

IMMUNOLOGY frviTfl". indue fam IjpocuJm 1 ftticfi. rdfiut. fit I Omega Ifu.dt |4 |

m^siigf"^"

rearr.Lambda Ch.

ONCOGENES & GFs Src'likc kin TFSLI

ONCOGENES & GFs Src'likc kin TFSLI

PROUH-RATION MAP Tau , Phusph 2A r crvtl ■scl.ljinq, Ca Ohwm I . MAItin pri'i K .

ll.il irtCp.fuiTUIlJ m

IMMUNOLOGY MHC »HIA IX-oB

I Ml A SB Alpha Ml.A-l) et II i-swot jr Gjimna-cii H2I0 ¡mfi-hirwlit. Milt" yjrl. Jflytiwrp, Ig riurT.tianaiiaf n. Ik ukut I -ambda eh Inldrl nuluu f*m '8 Alplu 2 ig-A

MH(MI HI_A't>R-Bl Hl.A-DR Alpha ht Ml KM I HKA-uP k

Oi!ii-i;,i Ehl ch Ome-gj tin ch h i Hu tjmbdu-17 done InJcrf.irahic. s)

UHL'ff.nwkli'. IjiJI

IMMUNOLOGY Polym (g, Leukm; is«*- rod Gram tol it i«l f«CI-Leufc<vyile üdtw s Hep i miir^ij.

CELL ADHESION l-nmimn S B.tch

-iktlm E| hnmul nie^firi Alpha- J dum jnnni'i Bj ch UGl'U nlegrin Bcia-t.

iidh^iin 1

Ri1x> iill IMMUNOLOGY Iii A B wiHuUck HI A I MHC I Ml«'I RlHOSOMAL R.I*.. U(. RihtJ. LIS • ;

Kihfi, 40S Li* Piit. Ril*> HL2J Riho. Miid. RilHV ImmiwI.

rriVWfff: Ih

TUMOR INHIBITORS TGF'BcU >iUgfrfiMn, ■

RIJUWOMAL R|Ih.I. Ribok L5 Rilhi I 14 Rib». (ivSK Wilni'vnim Rd. Rilni, 1.12 KIIhj

Oi!ii-i;,i Ehl ch Ome-gj tin ch h i Hu tjmbdu-17 done InJcrf.irahic. s)

UHL'ff.nwkli'. IjiJI

•2910 2910

Fig. 6.8 Hierarchical clustering of genes (rows) expressed in bladder cancers (columns). Yellow fields show up-regulation of genes (absolute difference in right panel, logfold change in left panel), blue fields show down-regulation of genes. (Figure by Christopher Workman using ClustArray software on data from Thykjaer et al., (2001) and postprocessing with Adobe Illustrator). (See color plate.)

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment