Parkinsonism may be associated with a wide range of underlying pathologies, in which the common feature is damage to the striatonigral system. In addition to the diseases discussed, virtually any pathological process that affects the striatonigral system has the potential to produce parkinsonism; these include various toxins (201-206), infections (207-212), mass lesions (213), and other conditions. As a result, neuropathological examination is essential for accurate diagnosis in an individual with clinical parkinsonism.

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