Future Research Issues

  1. Descriptive studies of the neuropsychiatric features in PSP, MSA, and CBD using standardized psychiatric rating scales.
  2. Study the diagnostic properties of the neuropsychiatric profile in parkinsonian disorders.
  3. Exploring the neurochemical underpinnings of neuropsychiatric symptoms in patients with parkinsonian disorders.
  4. In DLB, placebo-controlled trials of antidepressive and antipsychotic agents, and further trials of cho-linesterase inhibitors need to be conducted.
  5. In PSP, MSA, and CBD, pilot studies of the potential benefit of psychotropic agents are needed.
  6. Systematic studies of non-pharmacological strategies should be conducted for patients with parkinsonian disorders.

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