Calcium and Phosphate Homeostasis

Calcium and phosphate are used for much more than bone structure. Phosphate groups are a component of DNA, RNA, ATP, phospholipids, and many other compounds. Phosphate ions also help to correct acid-base imbalances in the body fluids (see insight 7.3). Calcium is needed for communication between neurons, muscle contraction, blood clotting, and exocytosis. It is also a second messenger in many cell signaling processes and a cofactor for some enzymes. The skeleton is a reservoir for these minerals. Minerals are deposited in the skeleton when the supply is ample and withdrawn when they are needed for other purposes.

Insight 7.3 Clinical Application

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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