In three cases, I felt that a subject could be presented more effectively by rearrangements and content substitutions within a chapter. Other chapters continue to be organized as they were in the second edition.
Chapter 1, Major Themes of Anatomy and Physiology
Here I replaced the section on human taxonomic classification with sections on anatomical and physiological variability. This gives the chapter a less zoological and more clinical flavor. Also, I feel it is important at the outset of such a course to instill a sense of the familiar roots of biomedical terms, the importance of precision in spelling, and other aspects of vocabulary. Thus I moved the former appendix B, which introduced students to medical etymology, to chapter 1 ("The Language of Medicine," p. 19).
Chapter 17, The Endocrine System
As many reviewers desired, I have separated endocrine pathology from normal physiology and placed the pathology at the end of the chapter.
Chapter 21, The Lymphatic and Immune Systems
I have found it more effective to present cellular immunity before humoral immunity, since humoral immunity depends on some concepts such as helper T cells usually introduced in the context of cellular immunity.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.