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3.27

Figure 3.26. The lateral view of the face strikingly demonstrates the marked nasal hypoplasia resulting in a very flat face. Because of the marked nasal hypoplasia these infants often present with upper airway obstruction.

Figure 3.27. Radiograph of the lower extremities of the same infant shows the stippling of die epiphyses at the proximal femora. Stippling of the epiphyses may occur along the vertebral column and the tarsal bones. The stippling disappears in die first few years of life. Coumadin™ embryopadiy is phenotypically similar to hereditary chondrodystrophia punctata and it must thus be distinguished from the different hereditary forms of Conradi-Hunermann syndrome.

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