Antibody Detection by Serology Assays

H. pylori specific IgG can be detected in infected patient serum samples by using ELISA assays. IgG-negative patient samples can be followed by detecting specific IgA antibodies. These assays are commercially available in both laboratory-based and point of care-based formats. They are easy to perform, relatively sensitive, and low cost. The disadvantage is that these antibodies may persist for months or years after eradication of the organism, and test results may need careful interpretation.

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