Androgen production in the ovary can also be blocked by gonadotropin-releasing hormone agonists such as buserelin, nafarelin, or leuprolide. These gonadotropin-releasing agonists block ovulation by interrupting the cyclic release of FSH and LH from the pituitary. These drugs are efficacious in acne and hirsutism, and are available as injectable drugs or nasal spray. However, in addition to suppressing the production of ovarian androgens, these drugs also suppress the ovarian production of estrogens, thereby eliminating the function of the ovary. Thus, the patient could develop meno-pausal symptoms and suffer from hypoestrogenism. Headaches can also develop, as well as the occurrence of bone loss, due to the reduction in estrogen.
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Headache Happiness! Stop Your Headache BEFORE IT STARTS. How To Get Rid Of Your Headache BEFORE It Starts! The pain can be AGONIZING Headaches can stop you from doing all the things you love. Seeing friends, playing with the kids... even trying to watch your favorite television shows. And just think of how unwelcome headaches are while you're trying to work.