Clinical features

Specific skin manifestations can be observed in approximately half of patients, especially those presenting with indolent forms of the disease [3-5]. Primary cutaneous involvement may also be seen [5]. Elderly men are affected more frequently. Anti-HTLV-I antibodies can be demonstrated in the serum of affected individuals. The clinical presentation resembles mycosis fungoides. Cutaneous lesions are localized or generalized macules and papules, plaques and tumours [3,4]. Erythroderma may also develop. A leukaemic blood picture and involvement of the bone marrow are found in more than half of patients. Spontaneous regression of skin lesions has been observed rarely [6].

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