Although the morphological features are those of a high-grade non-Hodgkin lymphoma, the prognosis of patients with primary cutaneous anaplastic large cell lymphoma is generally favourable. The estimated 5-year survival is over 90% [23,30,120]. Spontaneous regression and absence of extracu-taneous spread have been associated with a better prognosis .
It seems that patients presenting with skin tumours and evidence of specific lesions within regional lymph nodes at staging (concomitant cutaneous and nodal anaplastic large cell lymphoma) have a prognosis similar to that of patients with disease confined to the skin .
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