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Figure 1.61. In holoprosencephaly when there are separate orbits with a proboscis above the eyes and a lack of nostril with a single or double proboscis above or below the eyes, the condition is called ethmo-cephaly. Note also the small mouth.

Figure 1.62. Another variant of the median cleft syndrome (holoprosen-cephaly) is cebocephaly in which there is a small nose with a single nostril above or below the eyes. Note the single orifice and aplasia of the nasal septum and philtrum.

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