Hcv

Inhibit expression of viral mRNAfincrease resistance to virus

Viral mRNA/neighboring host cells

Ribavirin+Interferon-alpha

Piramaviruses (enteroviruses and rhinoviruses)

Inhibit attachment and uncoating of virus

Binds to virus

Pleconaril

CJW Cytomegalovirus; Mlfhur

nan immunodeficiency virus; HSV, herpes simplex virus; KZli varicella zos

1er virus; RSV, respiratory syncytial virus; HCV, hepatitis G vims.

they can reactivate, causing symptomatic, even fatal, disease.

adenoviruses

Adenoviruses (Table 51-4) were first isolated from human adenoid tissues. At present, approximately 50 serotypes of human adenoviruses have been described; however, most disease is associated with only one third of these types. Adenoviruses cause less than 5% of all acute respiratory disease in the general population, m. addition, adenovirus serotypes 40 and 41 cause gastro* enteritis in infants and young children, and other sero-type£\cause conjunctivitis and keratitis. Compromise^ hosts )may develop disseminated, multiorgan systems disease. Laboratory diagnosis is accomplished most corte monly by conventional or rapid cell culture using HEp-^ cells.

Table 51 -3 List of Viral Syndromes and Common Viral Pathogens

Viral Pathogens

Parainfluenza, respiratory syncytial, metapneumovlrus Respiratory syncytial, parainfluenza, metapneumovirus Respiratory syncytial, adenovirus, influenza, parainfluenza

Influenza, adenovirus, sin nombre virus (hantavirus), SARS Coronavirus

Norovinjses

Mumps, parainfluenza Coxsackie B and echoviruses

zoster, adenovirus, enterovirus 70

Coxsackie B

Coxsackie A

Encephalitis and other viruses

Viral Syndrome Intents and Children

Table 51 -4 Adenoviruses

Family: AdenoMiae

Virus: Adenovirus

Characteristics: Double-stranded DNA genome; icosahedral capsld.no envelope; approximately 50 human serotypes Transmission: Respiratory, fecal-oral, and direct contact (eye) wes

Site of latency: Replication in oropharynx

Prevention: Vaccine (adenovirus serotypes 4 and 7) for military recruits

Upper respiratory tract infection Pharyngitis

Parotitis

Myocarditis/pericarditis

Infectious mononucleosis

Meningitis

Rhinovirus, Coronavirus, adenovirus, influenza, parainfluenza, Epstein-Barr

Bronchitis

Upper respiratory tract infection

Pleurodynia

Hetpangina

Febrile illness with rash

Hemorrhagic cystitis Cutaneous infection with or without rash

Hemoirhagic fever Generalized, no specific target organ

Rhinovirus, Coronavirus, parainfluenza, adenovirus, respiratory syncytial, influenza Adenovirus, Coxsackie A herpes simplex, Epstein-Barr virus, riiinovirus, parainfluenza, influenza

Parainfluenza, respiratory syncytial, metapneumovlnjs

Rotavirus, adenovirus 40-41, calicivlrus, astrovims HSV-2, echovirus, and other enteroviruses, CMV, parvovirus B19, VZV, HIV, hepatitis viruses

Bronchiolitis Pneumonia

Gastroenteritis Congenital and neonatal disease

Adults

Pneumonia

Pleurodynia

All Patients enter0Vlruses'meas,e8'mMa' P^vovirus B-19, human herpesvirus 6 and 7, HPV poxviruses including smallpox, monkeypox, molluscum contegiosum. and orf

Epstein-Barr Vitus and cytomegalovirus

Echoviruses and coxsackie viruses, mumps, lymphocytic choriomeningitis, HSV-2 HSV-1, togaviruses, faunyaviruses, flaviviruses, rallies, enteroviruses, measles, HIV, JC virus Hepatitis A, B, C, D (delta agent), E, and non-A, B, C, D, E Adenovirus, BK virus

Table 51-6 Bunyaviruses

Table 51-5 Arenaviruses

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Bacterial Vaginosis Facts

Bacterial Vaginosis Facts

This fact sheet is designed to provide you with information on Bacterial Vaginosis. Bacterial vaginosis is an abnormal vaginal condition that is characterized by vaginal discharge and results from an overgrowth of atypical bacteria in the vagina.

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