The organisms discussed in this section require somewhat different conditions for their successful recovery from blood culture samples. Most of these organisms are infrequently isolated from blood. Therefore, it is important for the physidan to notify the laboratory of remarkable patient history, such as travel abroad, that is leading him or her to suspect these agents. In light of recent events and concerns about bioterrorism, it is also important that the laboratory be aware of organisms isolated from blood cultures that are considered potential agents for bioterrorist attacks. These bacteria indude Badllus anthrads, Francisella tularensis, Brucella spp., and Yersinia pestis. Finally, in addition to the organisms discussed below with different conditions for their successful isolation from blood, there are a number of organisms that do not grow on artifidal media and are best diagnosed by alternative methods such as serology or molecular amplification assays; these organisms are listed in Box 52-4.
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