Cottontail rabbit herpesvirus Synonym for leporid herpesvirus

Cottontail rabbit papillomavirus (Shope)

(CRPV) Type species of the genus Papillomavirus. The 72 capsomeres are arranged with a left-hand skew lattice. A natural infection of cottontail rabbits, Sylvilagus floridanus. Domestic rabbits, Oryctolagus, and several species of Lepus can be infected by scarification into the skin. Skin warts appear and regress but may become malignant, more often in domestic rabbits than in cottontails. Serial propagation in cell cultures has not been reported. Although rabbit erythrocytes adsorb the virus they are not agglutinated.

Synonym: Shope papillomavirus.

Bryan WR and Beard JW (1940) J Natl Cancer Inst 1, 607

Stevens JG and Wettstein FO (1979) J Virol 30, 891

Councilman-like bodies Collections of eosinophilic necrotic hyaline cells in the livers of yellow fever patients.

covalently closed circular DNA (cccDNA) A form of double-stranded DNA in which both strands are circular, i.e. do not have free ends. Also known as form I DNA. See supercoiled DNA.

Cowbone Ridge virus (CRV) A species in the genus Flavivirus, serologically belonging to the Modoc subgroup. No known arthropod vector. Isolated from a cotton rat in Florida, USA. Not reported to cause disease in humans.

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